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Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

BACKGROUND: Sarcopenia and osteoporosis are common diseases that predominantly affect older individuals. The interaction between muscle and skeleton exerts pivotal roles in bone remodeling. This study aimed to explore the function of myoblast-derived exosomal Prrx2 in osteogenic differentiation and...

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Detalles Bibliográficos
Autores principales: Li, Yunchao, Wang, Xiaoxiao, Pan, Changyu, Yuan, Hui, Li, Xinyi, Chen, Zejun, He, Haoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116833/
https://www.ncbi.nlm.nih.gov/pubmed/37081396
http://dx.doi.org/10.1186/s10020-023-00649-y