Cargando…

Myoblast-derived exosomal Prrx2 attenuates osteoporosis via transcriptional regulation of lncRNA-MIR22HG to activate Hippo pathway

BACKGROUND: Sarcopenia and osteoporosis are common diseases that predominantly affect older individuals. The interaction between muscle and skeleton exerts pivotal roles in bone remodeling. This study aimed to explore the function of myoblast-derived exosomal Prrx2 in osteogenic differentiation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yunchao, Wang, Xiaoxiao, Pan, Changyu, Yuan, Hui, Li, Xinyi, Chen, Zejun, He, Haoyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116833/ https://www.ncbi.nlm.nih.gov/pubmed/37081396 http://dx.doi.org/10.1186/s10020-023-00649-y

Ejemplares similares

gga-mir-133a-3p Regulates Myoblasts Proliferation and Differentiation by Targeting PRRX1
por: Guo, Lijin, et al.
Publicado: (2018)

LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism
por: He, Xin-yu, et al.
Publicado: (2023)

Long Noncoding RNA (lncRNA) MIR22HG Suppresses Gastric Cancer Progression through Attenuating NOTCH2 Signaling
por: Li, Huihui, et al.
Publicado: (2019)

Advances in Understanding the LncRNA-Mediated Regulation of the Hippo Pathway in Cancer
por: Wang, Mengwei, et al.
Publicado: (2021)

The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia
por: Bai, Xiao, et al.
Publicado: (2022)

M2 Macrophage-Derived Exosomal lncRNA MIR4435-2HG Promotes Progression of Infantile Hemangiomas by Targeting HNRNPA1
por: Li, Zhiyu, et al.
Publicado: (2023)

LncRNA MIR22HG promotes osteoarthritis progression via regulating miR-9-3p/ADAMTS5 pathway
por: Long, Hui, et al.
Publicado: (2021)

MIR31HG, a potential lncRNA in human cancers and non-cancers
por: Ruan, Luxi, et al.
Publicado: (2023)

LncRNA coordinates Hippo and mTORC1 pathway activation in cancer
por: Zhang, Shugeng, et al.
Publicado: (2021)

Hippo pathway inhibition promotes metabolic adaptability and antioxidant response in myoblasts
por: Liu, Qi, et al.
Publicado: (2023)

MIR100HG: a credible prognostic biomarker and an oncogenic lncRNA in gastric cancer
por: Li, Jun, et al.
Publicado: (2019)

Comparison of LncRNA Expression Profiles during Myogenic Differentiation and Adipogenic Transdifferentiation of Myoblasts
por: Qi, Renli, et al.
Publicado: (2019)

lncRNA MIR22HG-Derived miR-22-5p Enhances the Radiosensitivity of Hepatocellular Carcinoma by Increasing Histone Acetylation Through the Inhibition of HDAC2 Activity
por: Jin, Qiao, et al.
Publicado: (2021)

MIR22HG As A Tumor Suppressive lncRNA In HCC: A Comprehensive Analysis Integrating RT-qPCR, mRNA-Seq, And Microarrays
por: Gao, Li, et al.
Publicado: (2019)

Polymorphisms in lncRNA MIR2052HG and susceptibility to breast cancer in Chinese population
por: Yang, Hui, et al.
Publicado: (2021)

LncRNA MIR155HG Overexpression Promotes Proliferation, Migration, and Chemoresistance in Gastric Cancer Cells
por: Lin, Hong, et al.
Publicado: (2023)

LncRNA LINC00857 regulates the progression and glycolysis in ovarian cancer by modulating the Hippo signaling pathway
por: Lin, Xueke, et al.
Publicado: (2020)

LncRNA MIR4435-2HG is downregulated in osteoarthritis and regulates chondrocyte cell proliferation and apoptosis
por: Xiao, Yu, et al.
Publicado: (2019)

LncRNA MIR4435-2HG predicts poor prognosis in patients with colorectal cancer
por: Ouyang, Wen, et al.
Publicado: (2019)

The predictive value of lncRNA MIR31HG expression on clinical outcomes in patients with solid malignant tumors
por: Tu, Chao, et al.
Publicado: (2020)

Silencing of lncRNA MIR497HG via CRISPR/Cas13d Induces Bladder Cancer Progression Through Promoting the Crosstalk Between Hippo/Yap and TGF-β/Smad Signaling
por: Zhuang, Changshui, et al.
Publicado: (2020)

LncRNA MNX1-AS1 promotes progression of intrahepatic cholangiocarcinoma through the MNX1/Hippo axis
por: Li, Fengwei, et al.
Publicado: (2020)

Prediction of lncRNA–Protein Interactions via the Multiple Information Integration
por: Chen, Yifan, et al.
Publicado: (2021)

LncRNA-MIAT activates hepatic stellate cells via regulating Hippo pathway and epithelial-to-mesenchymal transition
por: Zhan, Yating, et al.
Publicado: (2023)

LncRNA PTCSC3 is upregulated in osteoporosis and negatively regulates osteoblast apoptosis
por: Liu, Xingchao, et al.
Publicado: (2022)

Corrigendum: Silencing of lncRNA MIR497HG via CRISPR/Cas13d Induces Bladder Cancer Progression Through Promoting the Crosstalk Between Hippo/Yap and TGF-β/Smad Signaling
por: Zhuang, Changshui, et al.
Publicado: (2021)

Exosomal miR-186 derived from BMSCs promote osteogenesis through hippo signaling pathway in postmenopausal osteoporosis
por: Li, Lu, et al.
Publicado: (2021)

Knockdown of lncRNA MIR31HG inhibits cell proliferation in human HaCaT keratinocytes
por: Gao, Jintao, et al.
Publicado: (2018)

The roles of miRNA, lncRNA and circRNA in the development of osteoporosis
por: Yang, Yang, et al.
Publicado: (2020)

Protective effect of hepatocyte-enriched lncRNA-Mir122hg by promoting hepatocyte proliferation in acute liver injury
por: Yu, Zhenjun, et al.
Publicado: (2022)

LncRNA MIR22HG abrogation inhibits proliferation and induces apoptosis in esophageal adenocarcinoma cells via activation of the STAT3/c-Myc/FAK signaling
por: Su, Wenmei, et al.
Publicado: (2019)

PRRX1 promotes malignant properties in human osteosarcoma
por: Joko, Ryoji, et al.
Publicado: (2020)

Exosomal miR-1298 and lncRNA-RP11-583F2.2 Expression in Hepato-cellular Carcinoma
por: Matboli, Marwa, et al.
Publicado: (2020)

Circulating exosomal lncRNA contributes to the pathogenesis of spinal cord injury in rats
por: Li, Jian-An, et al.
Publicado: (2022)

Emodin inhibits the progression of acute pancreatitis via regulation of lncRNA TUG1 and exosomal lncRNA TUG1
por: Wen, Xiumei, et al.
Publicado: (2021)

lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis
por: Wang, Shan-zheng, et al.
Publicado: (2021)

Hypoxia‐inducible lncRNA MIR210HG interacting with OCT1 is involved in glioblastoma multiforme malignancy
por: Ho, Kuo‐Hao, et al.
Publicado: (2021)

Biological Roles and Pathogenic Mechanisms of LncRNA MIR4435-2HG in Cancer: A Comprehensive Review
por: Chen, Zhou, et al.
Publicado: (2023)

A micropeptide encoded by lncRNA MIR155HG suppresses autoimmune inflammation via modulating antigen presentation
por: Niu, Liman, et al.
Publicado: (2020)

A novel cuproptosis-related prognostic lncRNA signature and lncRNA MIR31HG/miR-193a-3p/TNFRSF21 regulatory axis in lung adenocarcinoma
por: Mo, Xiaocong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j42897loi10redb6vbtasuu75o