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Identification of Efflux Substrates Using a Riboswitch-Based Reporter in Pseudomonas aeruginosa

Pseudomonas aeruginosa is intrinsically resistant to many classes of antibiotics, reflecting the restrictive nature of its outer membrane and the action of its numerous efflux systems. However, the dynamics of compound uptake, retention, and efflux in this bacterium remain incompletely understood. H...

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Detalles Bibliográficos
Autores principales: Urdaneta-Páez, Verónica, Hamchand, Randy, Anthony, Karen, Crawford, Jason, Sutherland, Alan G., Kazmierczak, Barbara I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117056/
https://www.ncbi.nlm.nih.gov/pubmed/36946743
http://dx.doi.org/10.1128/msphere.00069-23