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The E2F4/p130 Repressor Complex Cooperates with Oncogenic ΔNp73α To Inhibit Gene Expression in Human Papillomavirus 38 E6/E7-Transformed Keratinocytes and in Cancer Cells

Tumor suppressor p53 and its related proteins, p63 and p73, can be synthesized as multiple isoforms lacking part of the N- or C-terminal regions. Specifically, high expression of the ΔNp73α isoform is notoriously associated with various human malignancies characterized by poor prognosis. This isofor...

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Detalles Bibliográficos
Autores principales: Taverniti, Valerio, Krynska, Hanna, Venuti, Assunta, Straub, Marie-Laure, Sirand, Cécilia, Lohmann, Eugenie, Romero-Medina, Maria Carmen, Moro, Stefano, Robitaille, Alexis, Negroni, Luc, Martinez-Zapien, Denise, Masson, Murielle, Tommasino, Massimo, Zanier, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117100/
https://www.ncbi.nlm.nih.gov/pubmed/36883841
http://dx.doi.org/10.1128/msphere.00056-23