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Parkin regulates neuronal lipid homeostasis through SREBP2-lipoprotein lipase pathway—implications for Parkinson’s disease

Abnormal lipid homeostasis has been observed in the brain of Parkinson’s disease (PD) patients and experimental models, although the mechanism underlying this phenomenon is unclear. Notably, previous studies have reported that the PD-linked protein Parkin functionally interacts with important lipid...

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Detalles Bibliográficos
Autores principales: Tang, Willcyn, Thundyil, John, Lim, Grace Gui Yin, Tng, Teddy J W, Yeow, Sean Qing Zhang, Nair, Aditya, Chai, Chou, Yao, Tso-Pang, Lim, Kah-Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117165/
https://www.ncbi.nlm.nih.gov/pubmed/36519761
http://dx.doi.org/10.1093/hmg/ddac297