Cargando…

Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene

LI-cadherin is a member of the cadherin superfamily. LI-cadherin mediates Ca(2+)-dependent cell–cell adhesion through homodimerization. A previous study reported two single nucleotide polymorphisms (SNPs) in the LI-cadherin-coding gene (CDH17). These SNPs correspond to the amino acid changes of Lys1...

Descripción completa

Detalles Bibliográficos
Autores principales: Yui, Anna, Kuroda, Daisuke, Maruno, Takahiro, Nakakido, Makoto, Nagatoishi, Satoru, Uchiyama, Susumu, Tsumoto, Kouhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117238/
https://www.ncbi.nlm.nih.gov/pubmed/37081068
http://dx.doi.org/10.1038/s41598-023-32444-4