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Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene
LI-cadherin is a member of the cadherin superfamily. LI-cadherin mediates Ca(2+)-dependent cell–cell adhesion through homodimerization. A previous study reported two single nucleotide polymorphisms (SNPs) in the LI-cadherin-coding gene (CDH17). These SNPs correspond to the amino acid changes of Lys1...
Autores principales: | Yui, Anna, Kuroda, Daisuke, Maruno, Takahiro, Nakakido, Makoto, Nagatoishi, Satoru, Uchiyama, Susumu, Tsumoto, Kouhei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117238/ https://www.ncbi.nlm.nih.gov/pubmed/37081068 http://dx.doi.org/10.1038/s41598-023-32444-4 |
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