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A tissue specific-infection mouse model of SARS-CoV-2

Animal models play crucial roles in the rapid development of vaccines/drugs for the prevention and therapy of COVID-19, but current models have some deficits when studying the pathogenesis of SARS-CoV-2 on some special tissues or organs. Here, we generated a human ACE2 and SARS-CoV-2 N(F/F) knockin...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Liu, Chao, Ju, Xiaohui, Wu, Bingbing, Wang, Zhuangfei, Dong, Fucheng, Yu, Yanying, Hou, Xiaohui, Fang, Min, Gao, Fei, Guo, Xuejiang, Gui, Yaoting, Ding, Qiang, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117269/
https://www.ncbi.nlm.nih.gov/pubmed/37080957
http://dx.doi.org/10.1038/s41421-023-00536-0