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P(2)X and P2Y receptor antagonists reduce inflammation in ATP-induced microglia

BACKGROUND: P2 receptors have been implicated in the release of neurotransmitter and pro-inflammatory cytokines due to their response to neuro-excitatory substances in the microglia. The P2X4, P2X7 and P2Y12 receptors are involved in the development of pain behavior induced by peripheral nerve injur...

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Detalles Bibliográficos
Autores principales: Imraish, Amer, Abu-Thiab, Tuqa, Hammad, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Investigaciones y Publicaciones Farmaceuticas 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117305/
https://www.ncbi.nlm.nih.gov/pubmed/37090457
http://dx.doi.org/10.18549/PharmPract.2023.1.2788