C1q Confers Protection Against Cryptococcal Lung Infection by Alleviating Inflammation and Reducing Cryptococcal Virulence

BACKGROUND: To define the role of C1qa in host defense against Cryptococcus neoformans lung infection, we investigated its susceptibility to cryptococcal lung infection in mice deficient in complement factor C1qa (C1qa(−/−)). METHODS: We established a wild-type (WT) and C1qa-deficient murine inhalat...

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Detalles Bibliográficos
Autores principales: Zhao, Xu, Shen, Lei, Zheng, Jianming, Zhu, Haiyan, Li, Li, Shi, Hong, Chen, Zhongqing, Li, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Major Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117377/
https://www.ncbi.nlm.nih.gov/pubmed/37089772
http://dx.doi.org/10.1093/ofid/ofad151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117377/
https://www.ncbi.nlm.nih.gov/pubmed/37089772
http://dx.doi.org/10.1093/ofid/ofad151

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