Cargando…

C1q Confers Protection Against Cryptococcal Lung Infection by Alleviating Inflammation and Reducing Cryptococcal Virulence

BACKGROUND: To define the role of C1qa in host defense against Cryptococcus neoformans lung infection, we investigated its susceptibility to cryptococcal lung infection in mice deficient in complement factor C1qa (C1qa(−/−)). METHODS: We established a wild-type (WT) and C1qa-deficient murine inhalat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Xu, Shen, Lei, Zheng, Jianming, Zhu, Haiyan, Li, Li, Shi, Hong, Chen, Zhongqing, Li, Qian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Major Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117377/ https://www.ncbi.nlm.nih.gov/pubmed/37089772 http://dx.doi.org/10.1093/ofid/ofad151

Ejemplares similares

Evaluation of a Cryptococcal Antigen Lateral Flow Assay and Cryptococcal Antigen Positivity at a Large Public Hospital in Atlanta, Georgia
por: Harrington, Kristin R V, et al.
Publicado: (2021)

Microglia are not protective against cryptococcal meningitis
por: Mohamed, Sally H., et al.
Publicado: (2023)

Clinical Predictors Impacting Cryptococcal Dissemination and Poor Outcome in Patients With Cirrhosis
por: Cheng, Jia-Hui, et al.
Publicado: (2021)

Detrimental Outcomes of Unmasking Cryptococcal Meningitis With Recent ART Initiation
por: Rhein, Joshua, et al.
Publicado: (2018)

Association of Hyponatremia on Mortality in Cryptococcal Meningitis: A Prospective Cohort
por: Tugume, Lillian, et al.
Publicado: (2022)

Failure of Early Mycological Clearance in HIV-Negative Cryptococcal Meningitis
por: Su, Zhihui, et al.
Publicado: (2023)

Human Immune Response Varies by the Degree of Relative Cryptococcal Antigen Shedding
por: Boulware, David R., et al.
Publicado: (2015)

Cerebral Oximetry for Detecting High-mortality Risk Patients with Cryptococcal Meningitis
por: Diehl, John W, et al.
Publicado: (2018)

Seizures in Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: Predictors and Outcomes
por: Pastick, Katelyn A, et al.
Publicado: (2019)

High Burden of Cryptococcal Meningitis Among Antiretroviral Therapy–Experienced Human Immunodeficiency Virus–Infected Patients in Northern Uganda in the Era of “Test and Treat”: Implications for Cryptococcal Screening Programs
por: Okwir, Mark, et al.
Publicado: (2022)

Antibody Responses in HIV-Infected Patients With Advanced Immunosuppression and Asymptomatic Cryptococcal Antigenemia
por: Hlupeni, Admire, et al.
Publicado: (2018)

Baseline Serum C-Reactive Protein Level Predicts Mortality in Cryptococcal Meningitis
por: Chesdachai, Supavit, et al.
Publicado: (2020)

Cryptococcal Meningitis and Anti-virulence Therapeutic Strategies
por: Vu, Kiem, et al.
Publicado: (2019)

Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients
por: Nasri, Hashem, et al.
Publicado: (2016)

Acute Kidney Injury and Urinary Biomarkers in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis
por: Schutz, Charlotte, et al.
Publicado: (2017)

Cryptococcal Antigenemia in Nigerian Patients With Advanced Human Immunodeficiency Virus: Influence of Antiretroviral Therapy Adherence
por: Oladele, Rita O., et al.
Publicado: (2016)

Detection of High Cerebrospinal Fluid Levels of (1→3)-β-d-Glucan in Cryptococcal Meningitis
por: Rhein, Joshua, et al.
Publicado: (2014)

Prevalence of Cryptococcal Antigen and Outcomes in People With Human Immunodeficiency Virus in Honduras: A Cohort Study
por: Zuniga-Moya, Julio C, et al.
Publicado: (2020)

Cerebrospinal Fluid Culture Positivity and Clinical Outcomes After Amphotericin-Based Induction Therapy for Cryptococcal Meningitis
por: Rolfes, Melissa A., et al.
Publicado: (2015)

Epidemiology of Cryptococcosis and Cryptococcal Meningitis in a Large Retrospective Cohort of Patients After Solid Organ Transplantation
por: George, Ige A., et al.
Publicado: (2017)

Comparative Effectiveness of Induction Therapy for Human Immunodeficiency Virus-Associated Cryptococcal Meningitis: A Network Meta-Analysis
por: Campbell, Jeffrey I., et al.
Publicado: (2015)

Cryptococcal Antigenemia in Immunocompromised Human Immunodeficiency Virus Patients in Rural Tanzania: A Preventable Cause of Early Mortality
por: Letang, Emilio, et al.
Publicado: (2015)

Cryptococcal Antigen Screening Among Antiretroviral Therapy–Experienced People With HIV With Viral Load Nonsuppression in Rural Uganda
por: Baluku, Joseph Baruch, et al.
Publicado: (2021)

Therapeutic Lumbar Punctures in Human Immunodeficiency Virus–Associated Cryptococcal Meningitis: Should Opening Pressure Direct Management?
por: Kagimu, Enock, et al.
Publicado: (2022)

Underlying Cryptococcal Diseases and the Correlation With Serum Cryptococcal Antigen Titers in Hospitalized HIV-Infected Patients Screened Positive for Cryptococcal Antigenemia
por: Xu, Miaomiao, et al.
Publicado: (2020)

Neuro-Immune Mechanisms of Anti-Cryptococcal Protection
por: Drummond, Rebecca A.
Publicado: (2017)

Standardized Electrolyte Supplementation and Fluid Management Improves Survival During Amphotericin Therapy for Cryptococcal Meningitis in Resource-Limited Settings
por: Bahr, Nathan C., et al.
Publicado: (2014)

Accuracy of Noninvasive Intraocular Pressure or Optic Nerve Sheath Diameter Measurements for Predicting Elevated Intracranial Pressure in Cryptococcal Meningitis
por: Nabeta, Henry W., et al.
Publicado: (2014)

Cryptococcal Osteomyelitis in the Ribs
por: Sethi, Somika
Publicado: (2010)

The granuloma in cryptococcal disease
por: Ristow, Laura C., et al.
Publicado: (2021)

Symptomatic Cryptococcal Meningitis with Negative Serum and Cerebrospinal Fluid Cryptococcal Antigen Tests
por: Nanfuka, Vivien, et al.
Publicado: (2021)

Short-term Mortality Outcomes of HIV-Associated Cryptococcal Meningitis in Antiretroviral Therapy–Naïve and –Experienced Patients in Sub-Saharan Africa
por: Kalata, Newton, et al.
Publicado: (2021)

Systemic Approach to Virulence Gene Network Analysis for Gaining New Insight into Cryptococcal Virulence
por: Malachowski, Antoni N., et al.
Publicado: (2016)

Cryptococcal Virulence in Humans: Learning From Translational Studies With Clinical Isolates
por: de Sousa, Herdson Renney, et al.
Publicado: (2021)

Reciprocal modulation of ammonia and melanin production has implications for cryptococcal virulence
por: Baker, Rosanna P., et al.
Publicado: (2023)

Increased activity of the complement system in cerebrospinal fluid of the patients with Non-HIV Cryptococcal meningitis
por: Shen, Lei, et al.
Publicado: (2017)

Prevalence of Cryptococcal Antigenemia and Cost-Effectiveness of a Cryptococcal Antigen Screening Program – Vietnam
por: Smith, Rachel M., et al.
Publicado: (2013)

A Case of Cryptococcal Hepatitis in an HIV Patient with a Negative Serum Cryptococcal Antigen
por: Estifan, Elias, et al.
Publicado: (2019)

High Mortality in HIV-Associated Cryptococcal Meningitis Patients Treated With Amphotericin B–Based Therapy Under Routine Care Conditions in Africa
por: Patel, Raju K K, et al.
Publicado: (2018)

Cryptococcal 3-Hydroxy Fatty Acids Protect Cells Against Amoebal Phagocytosis
por: Madu, Uju L., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tc9hp1bjkkgkfc0o8v4j5ha4rr