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Fibronectin leucine-rich transmembrane protein 2 drives monocyte differentiation into macrophages via the UNC5B-Akt/mTOR axis

Upon migrating into the tissues, hematopoietic stem cell (HSC)-derived monocytes differentiate into macrophages, playing a crucial role in determining innate immune responses towards external pathogens and internal stimuli. However, the regulatory mechanisms underlying monocyte-to-macrophage differe...

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Detalles Bibliográficos
Autores principales: Fang, Yaxiong, Ma, Kongyang, Huang, Yi-Min, Dang, Yuanye, Liu, Zhaoyu, Xu, Yiming, Zheng, Xi-Long, Yang, Xiangdong, Huo, Yongliang, Dai, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117657/
https://www.ncbi.nlm.nih.gov/pubmed/37090697
http://dx.doi.org/10.3389/fimmu.2023.1162004