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The roles of serine hydrolases and serum albumin in alisol B 23-acetate hydrolysis in humans

Introduction: Alisol B 23-acetate (AB23A), a major bioactive constituent in the Chinese herb Zexie (Rhizoma Alismatis), has been found with multiple pharmacological activities. AB23A can be readily hydrolyzed to alisol B in mammals, but the hydrolytic pathways of AB23A in humans and the key enzymes...

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Detalles Bibliográficos
Autores principales: Zhang, Tiantian, Zhang, Feng, Zhang, Yani, Li, Hongxin, Zhu, Guanghao, Weng, Taotao, Huang, Cheng, Wang, Ping, He, Yuqi, Hu, Jing, Ge, Guangbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117764/
https://www.ncbi.nlm.nih.gov/pubmed/37089921
http://dx.doi.org/10.3389/fphar.2023.1160665