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Metabolic changes underlying drug resistance in the multiple myeloma tumor microenvironment

Multiple myeloma (MM) is characterized by the clonal expansion of malignant plasma cells in the bone marrow (BM). MM remains an incurable disease, with the majority of patients experiencing multiple relapses from different drugs. The MM tumor microenvironment (TME) and in particular bone-marrow stro...

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Detalles Bibliográficos
Autores principales: Matamala Montoya, María, van Slobbe, Gijs J. J., Chang, Jung-Chin, Zaal, Esther A., Berkers, Celia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117897/
https://www.ncbi.nlm.nih.gov/pubmed/37091139
http://dx.doi.org/10.3389/fonc.2023.1155621