Orthogonal analysis of variants in APOE gene using in-silico approaches reveals novel disrupting variants

Introduction: Alzheimer’s disease (AD) is one of the most prominent medical conditions in the world. Understanding the genetic component of the disease can greatly advance our knowledge regarding its progression, treatment and prognosis. Single amino-acid variants (SAVs) in the APOE gene have been w...

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Detalles Bibliográficos
Autores principales: Li, Chang, Hou, Ian, Ma, Mingjia, Wang, Grace, Bai, Yongsheng, Liu, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117898/
https://www.ncbi.nlm.nih.gov/pubmed/37091907
http://dx.doi.org/10.3389/fbinf.2023.1122559

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117898/
https://www.ncbi.nlm.nih.gov/pubmed/37091907
http://dx.doi.org/10.3389/fbinf.2023.1122559

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