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Orthogonal analysis of variants in APOE gene using in-silico approaches reveals novel disrupting variants
Introduction: Alzheimer’s disease (AD) is one of the most prominent medical conditions in the world. Understanding the genetic component of the disease can greatly advance our knowledge regarding its progression, treatment and prognosis. Single amino-acid variants (SAVs) in the APOE gene have been w...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117898/ https://www.ncbi.nlm.nih.gov/pubmed/37091907 http://dx.doi.org/10.3389/fbinf.2023.1122559 |