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Single-nucleotide resolution detection of Topo IV cleavage activity in the Escherichia coli genome with Topo-Seq
Topoisomerase IV (Topo IV) is the main decatenation enzyme in Escherichia coli; it removes catenation links that are formed during DNA replication. Topo IV binding and cleavage sites were previously identified in the E. coli genome with ChIP-Seq and NorfIP. Here, we used a more sensitive, single-nuc...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117906/ https://www.ncbi.nlm.nih.gov/pubmed/37089538 http://dx.doi.org/10.3389/fmicb.2023.1160736 |