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Cryo-EM tomography and automatic segmentation delineate modular structures in the postsynaptic density

Postsynaptic densities (PSDs) are large protein complexes associated with the postsynaptic membrane of excitatory synapses important for synaptic function including plasticity. Conventional electron microscopy (EM) typically depicts PSDs as compact disk-like structures of hundreds of nanometers in s...

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Detalles Bibliográficos
Autores principales: Jung, Jae Hoon, Chen, Xiaobing, Reese, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117989/
https://www.ncbi.nlm.nih.gov/pubmed/37091879
http://dx.doi.org/10.3389/fnsyn.2023.1123564