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Canine adipose tissue-derived MSCs engineered with mRNA to overexpress TSG-6 and enhance the anti-inflammatory effects in canine macrophages

BACKGROUND: Mesenchymal stem cells (MSCs) are useful agents in the treatment of various inflammatory diseases. The immunomodulatory effects of MSCs are largely related to their secretory properties. mRNA engineering emerged as a safe alternative to enhance the secretory function of MSCs. Optimizatio...

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Detalles Bibliográficos
Autores principales: Yun, Ga-Hee, Park, Su-Min, Lim, Ga-Hyun, Seo, Kyoung-Won, Youn, Hwa-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118014/
https://www.ncbi.nlm.nih.gov/pubmed/37089409
http://dx.doi.org/10.3389/fvets.2023.1134185