Hydroxycamptothecin regulates scar formation of the filtration channel under scleral flap by inhibiting the proliferation of scleral fibroblasts

BACKGROUND: To investigate the inhibitory effect of a hyaluronic acid hydrogel loaded with hydroxycamptothecin (HCPT) on scar formation after filtration surgery in a rabbit model. METHODS: Scleral fibroblasts were isolated and extracted from rabbits’ eyes. After treatment with different concentratio...

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Detalles Bibliográficos
Autores principales: Gu, Hongwei, Liang, Ya, Shen, Yao, Shuai, Jie, Yu, Qiuli, Guan, Huaijin, Yuan, Zhilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118090/
https://www.ncbi.nlm.nih.gov/pubmed/37079586
http://dx.doi.org/10.1371/journal.pone.0284618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118090/
https://www.ncbi.nlm.nih.gov/pubmed/37079586
http://dx.doi.org/10.1371/journal.pone.0284618

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