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Hydroxycamptothecin regulates scar formation of the filtration channel under scleral flap by inhibiting the proliferation of scleral fibroblasts
BACKGROUND: To investigate the inhibitory effect of a hyaluronic acid hydrogel loaded with hydroxycamptothecin (HCPT) on scar formation after filtration surgery in a rabbit model. METHODS: Scleral fibroblasts were isolated and extracted from rabbits’ eyes. After treatment with different concentratio...
Autores principales: | Gu, Hongwei, Liang, Ya, Shen, Yao, Shuai, Jie, Yu, Qiuli, Guan, Huaijin, Yuan, Zhilan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118090/ https://www.ncbi.nlm.nih.gov/pubmed/37079586 http://dx.doi.org/10.1371/journal.pone.0284618 |
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