Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects

BACKGROUND: The basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the first genome-wide analysis of genetic determinan...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Sehyun, Stockwell, Amy, Qin, Han, Gao, Simon S., Sagolla, Meredith, Stoilov, Ivaylo, Wuster, Arthur, Lai, Phillip, Yaspan, Brian L., Jeanne, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118094/
https://www.ncbi.nlm.nih.gov/pubmed/37079518
http://dx.doi.org/10.1371/journal.pone.0280484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118094/
https://www.ncbi.nlm.nih.gov/pubmed/37079518
http://dx.doi.org/10.1371/journal.pone.0280484

Ejemplares similares