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Rare CIDEC coding variants enriched in age-related macular degeneration patients with small low-luminance deficit cause lipid droplet and fat storage defects

BACKGROUND: The basis of Age-related macular degeneration (AMD) genetic risk has been well documented; however, few studies have looked at genetic biomarkers of disease progression or treatment response within advanced AMD patients. Here we report the first genome-wide analysis of genetic determinan...

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Detalles Bibliográficos
Autores principales:	Kim, Sehyun, Stockwell, Amy, Qin, Han, Gao, Simon S., Sagolla, Meredith, Stoilov, Ivaylo, Wuster, Arthur, Lai, Phillip, Yaspan, Brian L., Jeanne, Marion
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118094/ https://www.ncbi.nlm.nih.gov/pubmed/37079518 http://dx.doi.org/10.1371/journal.pone.0280484

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