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A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases

Genes associated with risk for brain disease exhibit characteristic expression patterns that reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of disease risk genes provide a molecular-based signature, based on differential co-expression, that is often unique to...

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Detalles Bibliográficos
Autores principales: Zeighami, Yashar, Bakken, Trygve E., Nickl-Jockschat, Thomas, Peterson, Zeru, Jegga, Anil G., Miller, Jeremy A., Schulkin, Jay, Evans, Alan C., Lein, Ed S., Hawrylycz, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118126/
https://www.ncbi.nlm.nih.gov/pubmed/37079537
http://dx.doi.org/10.1371/journal.pbio.3002058