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A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases
Genes associated with risk for brain disease exhibit characteristic expression patterns that reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of disease risk genes provide a molecular-based signature, based on differential co-expression, that is often unique to...
Autores principales: | Zeighami, Yashar, Bakken, Trygve E., Nickl-Jockschat, Thomas, Peterson, Zeru, Jegga, Anil G., Miller, Jeremy A., Schulkin, Jay, Evans, Alan C., Lein, Ed S., Hawrylycz, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118126/ https://www.ncbi.nlm.nih.gov/pubmed/37079537 http://dx.doi.org/10.1371/journal.pbio.3002058 |
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