Effect of stimulator of interferon genes (STING) signaling on radiation-induced chemokine expression in human osteosarcoma cells

Cancer cell-intrinsic mechanisms affecting radiation immunomodulation could be exploited to optimize systemic effects of localized radiation. Radiation-induced DNA damage is sensed by cyclic GMP-AMP synthase (cGAS), which ultimately activates stimulator of interferon (IFN) genes (STING). Resultant e...

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Detalles Bibliográficos
Autores principales: Withers, Sita S., Moeller, Cambri E., Quick, Cally N., Liu, Chin-Chi, Baham, Shelby M., Looper, Jayme S., Subramanian, Ramesh, Kousoulas, Konstantin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118169/
https://www.ncbi.nlm.nih.gov/pubmed/37079538
http://dx.doi.org/10.1371/journal.pone.0284645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118169/
https://www.ncbi.nlm.nih.gov/pubmed/37079538
http://dx.doi.org/10.1371/journal.pone.0284645

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