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Tannic acid, an IL-1β-direct binding compound, ameliorates IL-1β-induced inflammation and cartilage degradation by hindering IL-1β-IL-1R1 interaction

Interleukin-1β (IL-1β) is one of the most potent pro-inflammatory cytokines implicated in a wide range of autoinflammatory, autoimmune, infectious, and degenerative diseases. Therefore, many researchers have focused on developing therapeutic molecules that inhibit IL-1β-IL-1 receptor 1 (IL-1R1) inte...

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Detalles Bibliográficos
Autores principales: Lee, Hae-Ri, Jeong, Young-Jin, Lee, Joong-Woon, Jhun, JooYeon, Na, Hyun Sik, Cho, Keun-Hyung, Kim, Seok Jung, Cho, Mi-La, Heo, Tae-Hwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118179/
https://www.ncbi.nlm.nih.gov/pubmed/37079558
http://dx.doi.org/10.1371/journal.pone.0281834