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Regenerative Capability of Human Nucleus Pulposus Cells in Degenerated Disc Under Hydrostatic Pressure Mimicking Physiologically Relevant Intradiscal Pressure In Vitro

Isolated human nucleus pulposus (hNP) cells from the degenerated intervertebral disc (IVD) were incubated under hydrostatic pressure (HP) and evaluated for regenerative potential. OBJECTIVES. To characterize metabolic turnover in hNP cells isolated from degenerated IVDs classified by Pfirrmann grade...

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Detalles Bibliográficos
Autores principales: Takeoka, Yoshiki, Kanda, Yutaro, Kang, James D., Mizuno, Shuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118243/
https://www.ncbi.nlm.nih.gov/pubmed/36856558
http://dx.doi.org/10.1097/BRS.0000000000004530