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An Assessment of Quaternary Structure Functionality in Homomer Protein Complexes
It has been recently suggested that a significant fraction of homomer protein–protein interfaces evolve neutrally, without contributing to function, due to a hydrophobic bias in missense mutations. However, the fraction of such gratuitous complexes is currently unknown. Here, we quantified the fract...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118308/ https://www.ncbi.nlm.nih.gov/pubmed/36947103 http://dx.doi.org/10.1093/molbev/msad070 |