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An Assessment of Quaternary Structure Functionality in Homomer Protein Complexes

It has been recently suggested that a significant fraction of homomer protein–protein interfaces evolve neutrally, without contributing to function, due to a hydrophobic bias in missense mutations. However, the fraction of such gratuitous complexes is currently unknown. Here, we quantified the fract...

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Detalles Bibliográficos
Autores principales: Abrusán, György, Foguet, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118308/
https://www.ncbi.nlm.nih.gov/pubmed/36947103
http://dx.doi.org/10.1093/molbev/msad070