Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophila cells

Loss-of-function and gain-of-function genetic perturbations provide valuable insights into gene function. In Drosophila cells, while genome-wide loss-of-function screens have been extensively used to reveal mechanisms of a variety of biological processes, approaches for performing genome-wide gain-o...

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Detalles Bibliográficos
Autores principales: Xia, Baolong, Viswanatha, Raghuvir, Hu, Yanhui, Mohr, Stephanie E, Perrimon, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118385/
https://www.ncbi.nlm.nih.gov/pubmed/37078570
http://dx.doi.org/10.7554/eLife.85542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118385/
https://www.ncbi.nlm.nih.gov/pubmed/37078570
http://dx.doi.org/10.7554/eLife.85542

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