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Pooled genome-wide CRISPR activation screening for rapamycin resistance genes in Drosophila cells
Loss-of-function and gain-of-function genetic perturbations provide valuable insights into gene function. In Drosophila cells, while genome-wide loss-of-function screens have been extensively used to reveal mechanisms of a variety of biological processes, approaches for performing genome-wide gain-o...
Autores principales: | Xia, Baolong, Viswanatha, Raghuvir, Hu, Yanhui, Mohr, Stephanie E, Perrimon, Norbert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118385/ https://www.ncbi.nlm.nih.gov/pubmed/37078570 http://dx.doi.org/10.7554/eLife.85542 |
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