Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome

BACKGROUND: Genome-wide association studies (GWASs) have identified genetic susceptibility variants for both leukocyte telomere length (LTL) and lung cancer susceptibility. Our study aims to explore the shared genetic basis between these traits and investigate their impact on somatic environment of...

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Detalles Bibliográficos
Autores principales: Cortez Cardoso Penha, Ricardo, Smith-Byrne, Karl, Atkins, Joshua R, Haycock, Philip C, Kar, Siddhartha, Codd, Veryan, Samani, Nilesh J, Nelson, Christopher, Milojevic, Maja, Gabriel, Aurélie AG, Amos, Christopher, Brennan, Paul, Hung, Rayjean J, Kachuri, Linda, Mckay, James D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Epidemiology and Global Health
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118386/
https://www.ncbi.nlm.nih.gov/pubmed/37079368
http://dx.doi.org/10.7554/eLife.83118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118386/
https://www.ncbi.nlm.nih.gov/pubmed/37079368
http://dx.doi.org/10.7554/eLife.83118

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