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Paraoxonase 1 (PON1) Q192R genotypes and their interaction with smoking strongly increase atherogenicity and the Framingham risk score

OBJECTIVE: Paraoxonase 1 (PON1) polymorphisms are associated with an increased susceptibility to cardiovascular disease. PON1 Q192R polymorphism (rs662) partially determine PON1 hydrolytic activity and protect against oxidation of LDL and HDL. This study aimed to delineate the association of PON1 st...

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Detalles Bibliográficos
Autores principales: de Souza-Nogueira, Andre, Camargo, Alissana Ester, Remondi, Felipe Assan, Paoliello, Monica Maria Bastos, Richter, Rebecca J., Furlong, Clement E., Barbosa, Decio Sabbatini, Maes, Michael, Moreira, Estefania Gastaldello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118632/
https://www.ncbi.nlm.nih.gov/pubmed/27812605
http://dx.doi.org/10.1590/2359-3997000000184