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Proteostasis failure exacerbates neuronal circuit dysfunction and sleep impairments in Alzheimer’s disease

Failed proteostasis is a well-documented feature of Alzheimer’s disease, particularly, reduced protein degradation and clearance. However, the contribution of failed proteostasis to neuronal circuit dysfunction is an emerging concept in neurodegenerative research and will prove critical in understan...

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Detalles Bibliográficos
Autores principales: Morrone, Christopher Daniel, Raghuraman, Radha, Hussaini, S. Abid, Yu, Wai Haung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119020/
https://www.ncbi.nlm.nih.gov/pubmed/37085942
http://dx.doi.org/10.1186/s13024-023-00617-4