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[(18)F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT(1A) receptors in humans

PURPOSE: F13640 (a.k.a. befiradol, NLX-112) is a highly selective 5-HT(1A) receptor ligand that was selected as a PET radiopharmaceutical-candidate based on animal studies. Due to its high efficacy agonist properties, [(18)F]F13640 binds preferentially to functional 5-HT(1A) receptors, which are cou...

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Detalles Bibliográficos
Autores principales: Courault, Pierre, Lancelot, Sophie, Costes, Nicolas, Colom, Matthieu, Le Bars, Didier, Redoute, Jérôme, Gobert, Florent, Dailler, Frédéric, Isal, Sibel, Iecker, Thibaut, Newman-Tancredi, Adrian, Merida, Inés, Zimmer, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119077/
https://www.ncbi.nlm.nih.gov/pubmed/36656363
http://dx.doi.org/10.1007/s00259-022-06103-1