Cargando…

[(18)F]F13640: a selective agonist PET radiopharmaceutical for imaging functional 5-HT(1A) receptors in humans

PURPOSE: F13640 (a.k.a. befiradol, NLX-112) is a highly selective 5-HT(1A) receptor ligand that was selected as a PET radiopharmaceutical-candidate based on animal studies. Due to its high efficacy agonist properties, [(18)F]F13640 binds preferentially to functional 5-HT(1A) receptors, which are cou...

Descripción completa

Detalles Bibliográficos
Autores principales:	Courault, Pierre, Lancelot, Sophie, Costes, Nicolas, Colom, Matthieu, Le Bars, Didier, Redoute, Jérôme, Gobert, Florent, Dailler, Frédéric, Isal, Sibel, Iecker, Thibaut, Newman-Tancredi, Adrian, Merida, Inés, Zimmer, Luc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119077/ https://www.ncbi.nlm.nih.gov/pubmed/36656363 http://dx.doi.org/10.1007/s00259-022-06103-1

Ejemplares similares

[(18)F]F13640, a 5-HT(1A) Receptor Radiopharmaceutical Sensitive to Brain Serotonin Fluctuations
por: Colom, Matthieu, et al.
Publicado: (2021)

CERMEP-IDB-MRXFDG: a database of 37 normal adult human brain [(18)F]FDG PET, T1 and FLAIR MRI, and CT images available for research
por: Mérida, Inés, et al.
Publicado: (2021)

Distribution of α(2)-Adrenergic Receptors in the Living Human Brain Using [(11)C]yohimbine PET
por: Laurencin, Chloé, et al.
Publicado: (2023)

Selective serotonin 5-HT(1A) receptor biased agonists elicitdistinct brain activation patterns: a pharmacoMRI study
por: Becker, G., et al.
Publicado: (2016)

Design of CGMP Production of (18)F- and (68)Ga-Radiopharmaceuticals
por: Chi, Yen-Ting, et al.
Publicado: (2014)

Characterization and Reliability of [(18)F]2FNQ1P in Cynomolgus Monkeys as a PET Radiotracer for Serotonin 5-HT(6) Receptors
por: Sgambato-Faure, Véronique, et al.
Publicado: (2017)

Marmoset Serotonin 5-HT(1A) Receptor Mapping with a Biased Agonist PET Probe (18)F-F13714: Comparison with an Antagonist Tracer (18)F-MPPF in Awake and Anesthetized States
por: Yokoyama, Chihiro, et al.
Publicado: (2016)

Spatio-Temporal Characterization of Brain Inflammation in a Non-human Primate Stroke Model Mimicking Endovascular Thrombectomy
por: Becker, Guillaume, et al.
Publicado: (2023)

[(18)F]Tosyl fluoride as a versatile [(18)F]fluoride source for the preparation of (18)F-labeled radiopharmaceuticals
por: Zhou, Dong, et al.
Publicado: (2023)

Corrigendum to “Design of CGMP Production of (18)F- and (68)Ga-Radiopharmaceuticals”
por: Chi, Yen-Ting, et al.
Publicado: (2016)

Good practices for the automated production of (18)F-SiFA radiopharmaceuticals
por: Blok, Simon, et al.
Publicado: (2023)

A Fast and Simple Method for the Determination of TBA in (18)F-Labeled Radiopharmaceuticals
por: Halvorsen, Nils Erik, et al.
Publicado: (2020)

Bayesian Estimation of the ntPET Model in Single-Scan Competition PET Studies
por: Irace, Zacharie, et al.
Publicado: (2020)

Frontal Transcranial Direct Current Stimulation Induces Dopamine Release in the Ventral Striatum in Human
por: Fonteneau, Clara, et al.
Publicado: (2018)

Anti-aggressive effects of the selective high-efficacy ‘biased’ 5-HT(1A) receptor agonists F15599 and F13714 in male WTG rats
por: de Boer, Sietse F., et al.
Publicado: (2015)

(18)F-Fluorodihydroxyphenylalanine vs other radiopharmaceuticals for imaging neuroendocrine tumours according to their type
por: Balogova, Sona, et al.
Publicado: (2013)

Recent Advances in the Clinical Translation of Silicon Fluoride Acceptor (SiFA) (18)F-Radiopharmaceuticals
por: Gower-Fry, Lexi, et al.
Publicado: (2021)

5-HT(1A )gene promoter polymorphism and [(18)F]MPPF binding potential in healthy subjects: a PET study
por: Lothe, Amélie, et al.
Publicado: (2010)

Targeted 5-HT(1F) Therapies for Migraine
por: Vila-Pueyo, Marta
Publicado: (2018)

(18)F-Labeled Silicon-Based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals
por: Bernard-Gauthier, Vadim, et al.
Publicado: (2014)

Radioprotective efficacy of plastic polymer against the toxicogenomic effects of radiopharmaceutical (18)F-FDG on human lymphocytes
por: Lopes, Nilson Benedito, et al.
Publicado: (2020)

Embryo/Fetus Doses from (18)F-Fludeoxyglucose Radiopharmaceutical in Positron Emission Tomography/ Computed Tomography
por: Işıkçı, Nazenin İpek, et al.
Publicado: (2022)

PET-MRI nanoparticles imaging of blood–brain barrier damage and modulation after stroke reperfusion
por: Debatisse, Justine, et al.
Publicado: (2020)

N-Benzylethanolammonium Ionic Liquids and Molten Salts in the Synthesis of (68)Ga- and Al(18)F-Labeled Radiopharmaceuticals
por: Kondratenko, Yulia A., et al.
Publicado: (2023)

PET imaging of (68)Ga-NODAGA-RGD, as compared with (18)F-fluorodeoxyglucose, in experimental rodent models of engrafted glioblastoma
por: Isal, Sibel, et al.
Publicado: (2018)

Radiopharmaceuticals for therapy
por: Knapp, F F (Russ), et al.
Publicado: (2016)

PET Radiopharmaceuticals
por: Shahhosseini, Soraya
Publicado: (2011)

Pharmacovigilance in radiopharmaceuticals
por: Kumar, Rishi, et al.
Publicado: (2016)

Role of 2-[(18)F]FDG as a Radiopharmaceutical for PET/CT in Patients with COVID-19: A Systematic Review
por: Annunziata, Salvatore, et al.
Publicado: (2020)

Digital PET/CT allows for shorter acquisition protocols or reduced radiopharmaceutical dose in [(18)F]-FDG PET/CT
por: Alberts, Ian, et al.
Publicado: (2021)

3p-C-NETA: A versatile and effective chelator for development of Al(18)F-labeled and therapeutic radiopharmaceuticals
por: Ahenkorah, Stephen, et al.
Publicado: (2022)

Towards in vivo imaging of functionally active 5-HT(1A) receptors in schizophrenia: concepts and challenges
por: Razakarivony, Oriane, et al.
Publicado: (2021)

The selective 5-HT(1A) receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress
por: Głuch-Lutwin, Monika, et al.
Publicado: (2021)

Radiopharmaceuticals in monitoring cancer
por: Britton, Keith E., et al.
Publicado: (2015)

Are we “preparing” radiopharmaceuticals?
por: Decristoforo, Clemens, et al.
Publicado: (2016)

New SPECT and PET Radiopharmaceuticals for Imaging Cardiovascular Disease
por: Sogbein, Oyebola O., et al.
Publicado: (2014)

Distribution of 5-HT(1F) Receptors in Monkey Vestibular and Trigeminal Ganglion Cells
por: Usman, Habiba O., et al.
Publicado: (2016)

Sex differences in aggression: Differential roles of 5-HT(2), neuropeptide F and tachykinin
por: Bubak, Andrew N., et al.
Publicado: (2019)

Lasmiditan mechanism of action – review of a selective 5-HT(1F) agonist
por: Clemow, David B., et al.
Publicado: (2020)

CGRP Receptor Antagonists and 5-HT1F Receptor Agonist in the Treatment of Migraine
por: Capi, Matilde, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4c9aaa9mckf01bnupqnjl5da40