Recreation of an antigen-driven germinal center in vitro by providing B cells with phagocytic antigen

Successful vaccines rely on activating a functional humoral immune response through the generation of class-switched high affinity immunoglobulins (Igs). The germinal center (GC) reaction is crucial for this process, in which B cells are selected in their search for antigen and T cell help. A major...

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Detalles Bibliográficos
Autores principales: Martínez-Riaño, Ana, Delgado, Pilar, Tercero, Rut, Barrero, Sara, Mendoza, Pilar, Oeste, Clara L., Abia, David, Rodríguez-Bovolenta, Elena, Turner, Martin, Alarcón, Balbino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119099/
https://www.ncbi.nlm.nih.gov/pubmed/37081131
http://dx.doi.org/10.1038/s42003-023-04807-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119099/
https://www.ncbi.nlm.nih.gov/pubmed/37081131
http://dx.doi.org/10.1038/s42003-023-04807-0

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