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Immunodetection of Pyruvate Carboxylase Expression in Human Astrocytomas, Glioblastomas, Oligodendrogliomas, and Meningiomas

Pyruvate carboxylase (PC) is an enzyme catalyzing the carboxylation of pyruvate to oxaloacetate. The enzymatic generation of oxaloacetate, an intermediate of the Krebs cycle, could provide the cancer cells with the additional anaplerotic capacity and promote their anabolic metabolism. Recent studies...

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Detalles Bibliográficos
Autores principales: Gondáš, Eduard, Kráľová Trančíková, Alžbeta, Dibdiaková, Katarina, Galanda, Tomáš, Hatok, Jozef, Račay, Peter, Dobrota, Dušan, Murín, Radovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119210/
https://www.ncbi.nlm.nih.gov/pubmed/36662405
http://dx.doi.org/10.1007/s11064-023-03856-5