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NOX4-derived ROS are neuroprotective by balancing intracellular calcium stores

Hyperexcitability is associated with neuronal dysfunction, cellular death, and consequently neurodegeneration. Redox disbalance can contribute to hyperexcitation and increased reactive oxygen species (ROS) levels are observed in various neurological diseases. NOX4 is an NADPH oxidase known to produc...

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Detalles Bibliográficos
Autores principales: Gola, Lukas, Bierhansl, Laura, Csatári, Júlia, Schroeter, Christina B., Korn, Lisanne, Narayanan, Venu, Cerina, Manuela, Abdolahi, Sara, Speicher, Anna, Hermann, Alexander M., König, Simone, Dinkova-Kostova, Albena T., Shekh-Ahmad, Tawfeeq, Meuth, Sven G., Wiendl, Heinz, Gorji, Ali, Pawlowski, Matthias, Kovac, Stjepana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119225/
https://www.ncbi.nlm.nih.gov/pubmed/37081190
http://dx.doi.org/10.1007/s00018-023-04758-z