Urinary tract infections trigger synucleinopathy via the innate immune response

Symptoms in the urogenital organs are common in multiple system atrophy (MSA), also in the years preceding the MSA diagnosis. It is unknown how MSA is triggered and these observations in prodromal MSA led us to hypothesize that synucleinopathy could be triggered by infection of the genitourinary tra...

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Detalles Bibliográficos
Autores principales: Peelaerts, Wouter, Mercado, Gabriela, George, Sonia, Villumsen, Marie, Kasen, Alysa, Aguileta, Miguel, Linstow, Christian, Sutter, Alexandra B., Kuhn, Emily, Stetzik, Lucas, Sheridan, Rachel, Bergkvist, Liza, Meyerdirk, Lindsay, Lindqvist, Allison, Gavis, Martha L. Escobar, Van den Haute, Chris, Hultgren, Scott J., Baekelandt, Veerle, Pospisilik, J. Andrew, Brudek, Tomasz, Aznar, Susana, Steiner, Jennifer A., Henderson, Michael X., Brundin, Lena, Ivanova, Magdalena I., Hannan, Tom J., Brundin, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119259/
https://www.ncbi.nlm.nih.gov/pubmed/36991261
http://dx.doi.org/10.1007/s00401-023-02562-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119259/
https://www.ncbi.nlm.nih.gov/pubmed/36991261
http://dx.doi.org/10.1007/s00401-023-02562-4

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