HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility

BACKGROUND: Metabolic disorder is an essential characteristic of tumor development. Ketogenesis is a heterogeneous factor in multiple cancers, but the effect of ketogenesis on hepatocellular carcinoma (HCC) is elusive. METHODS: We aimed to explain the role of ketogenesis-related hydroxy-methyl-gluta...

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Detalles Bibliográficos
Autores principales: Cui, Xiaohan, Yun, Xiao, Sun, Meiling, Li, Renzhi, Lyu, Xiajie, Lao, Yuanxiang, Qin, Xihu, Yu, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119270/
https://www.ncbi.nlm.nih.gov/pubmed/36508088
http://dx.doi.org/10.1007/s12072-022-10459-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119270/
https://www.ncbi.nlm.nih.gov/pubmed/36508088
http://dx.doi.org/10.1007/s12072-022-10459-9

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