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Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos

Bulky cargos like procollagens, apolipoproteins, and mucins exceed the size of conventional COPII vesicles. During evolution a process emerged in metazoans, predominantly governed by the TANGO1 protein family, that organizes cargo at the exit sites of the endoplasmic reticulum and facilitates export...

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Detalles Bibliográficos
Autores principales: Arnolds, Oliver, Stoll, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119292/
https://www.ncbi.nlm.nih.gov/pubmed/37080980
http://dx.doi.org/10.1038/s41467-023-37705-4