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Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos
Bulky cargos like procollagens, apolipoproteins, and mucins exceed the size of conventional COPII vesicles. During evolution a process emerged in metazoans, predominantly governed by the TANGO1 protein family, that organizes cargo at the exit sites of the endoplasmic reticulum and facilitates export...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119292/ https://www.ncbi.nlm.nih.gov/pubmed/37080980 http://dx.doi.org/10.1038/s41467-023-37705-4 |