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Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function

The specification of the forebrain relies on the precise regulation of WNT/ß-catenin signalling to support neuronal progenitor cell expansion, patterning, and morphogenesis. Imbalances in WNT signalling activity in the early neuroepithelium lead to congenital disorders, such as neural tube defects (...

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Detalles Bibliográficos
Autores principales: Geng, Shuang, Paul, Fabian, Kowalczyk, Izabela, Raimundo, Sandra, Sporbert, Anje, Mamo, Tamrat Meshka, Hammes, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119419/
https://www.ncbi.nlm.nih.gov/pubmed/37091972
http://dx.doi.org/10.3389/fcell.2023.1173688