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Evolution of immunogenetic components encoding ultralong CDR H3

The genomes of most vertebrates contain many V, D, and J gene segments within their Ig loci to construct highly variable CDR3 sequences through combinatorial diversity. This nucleotide variability translates into an antibody population containing extensive paratope diversity. Cattle have relatively...

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Detalles Bibliográficos
Autores principales: Ott, Jeannine A., Mitchell, Christian, Sheppard, Morgan, Deiss, Thad C., Horton, J. M. Cody, Haakenson, Jeremy K., Huang, Ruiqi, Kelley, Abigail R., Davis, Brian W., Derr, James N., Smider, Vaughn V., Criscitiello, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119515/
https://www.ncbi.nlm.nih.gov/pubmed/37084012
http://dx.doi.org/10.1007/s00251-023-01305-9