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A mouse model characterizes the roles of ZIP8 in systemic iron recycling and lung inflammation and infection

ZIP8 (SLC39A8) is a transmembrane divalent metal ion importer that is most highly expressed in the lung and is inducible by inflammatory stimuli. In addition to zinc and manganese, ZIP8 can transport iron, but its specific roles in iron regulation during homeostatic and pathologic processes remain p...

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Detalles Bibliográficos
Autores principales: Zhang, Vida, Jenkitkasemwong, Supak, Liu, Qingli, Ganz, Tomas, Nemeth, Elizabeta, Knutson, Mitchell D., Kim, Airie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119600/
https://www.ncbi.nlm.nih.gov/pubmed/36260707
http://dx.doi.org/10.1182/bloodadvances.2022007867