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Calpain inhibitor MDL28170 alleviates cerebral ischemia‑reperfusion injury by suppressing inflammation and autophagy in a rat model of cardiac arrest

Cerebral ischemia-reperfusion injury (CIRI) is associated with a poor neurological prognosis in patients who have experienced cardiac arrest (CA) and cardiopulmonary resuscitation (CPR). The aim of the current study was to investigate the potential role of a calpain inhibitor in CIRI using a rat mod...

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Detalles Bibliográficos
Autores principales: Wang, Wen-Yan, Shi, Jia-Xin, Chen, Meng-Hua, Zhuge, Xiang-Zhen, Dai, Chun-Guang, Xie, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119620/
https://www.ncbi.nlm.nih.gov/pubmed/37090078
http://dx.doi.org/10.3892/etm.2023.11895