Oxymatrine inhibits TGF‑β1‑mediated mitochondrial apoptotic signaling in alveolar epithelial cells via activation of PI3K/AKT signaling

Although pulmonary fibrosis (PF) causes respiratory failure and death, effective therapies for PF have not been developed. Oxymatrine (OMT), an active ingredient in the Chinese herb Sophora flavescens, exerts antifibrotic effects; however, its effect on PF remains unclear. The present study aimed to...

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Detalles Bibliográficos
Autores principales: Feng, Tong, Duan, Ran, Zheng, Pengcheng, Qiu, Jing, Li, Qingyuan, Li, Wancheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119625/
https://www.ncbi.nlm.nih.gov/pubmed/37090069
http://dx.doi.org/10.3892/etm.2023.11897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119625/
https://www.ncbi.nlm.nih.gov/pubmed/37090069
http://dx.doi.org/10.3892/etm.2023.11897

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