Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition

Platelet glycoprotein VI (GPVI) is attracting interest as a potential target for the development of new antiplatelet molecules with a low bleeding risk. GPVI binding to vascular collagen initiates thrombus formation and GPVI interactions with fibrin promote the growth and stability of the thrombus....

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Detalles Bibliográficos
Autores principales: Billiald, Philippe, Slater, Alexandre, Welin, Martin, Clark, Joanne C., Loyau, Stéphane, Pugnière, Martine, Jiacomini, Isabella G., Rose, Nadia, Lebozec, Kristell, Toledano, Elie, François, Déborah, Watson, Steve P., Jandrot-Perrus, Martine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119634/
https://www.ncbi.nlm.nih.gov/pubmed/36375047
http://dx.doi.org/10.1182/bloodadvances.2022007863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119634/
https://www.ncbi.nlm.nih.gov/pubmed/36375047
http://dx.doi.org/10.1182/bloodadvances.2022007863

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