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Evolutionary Engineering of a Cp*Rh(III) Complex-Linked Artificial Metalloenzyme with a Chimeric β-Barrel Protein Scaffold

[Image: see text] Evolutionary engineering of our previously reported Cp*Rh(III)-linked artificial metalloenzyme was performed based on a DNA recombination strategy to improve its catalytic activity toward C(sp(2))–H bond functionalization. Improved scaffold design was achieved with α-helical cap do...

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Detalles Bibliográficos
Autores principales: Kato, Shunsuke, Onoda, Akira, Schwaneberg, Ulrich, Hayashi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10119979/
https://www.ncbi.nlm.nih.gov/pubmed/36892401
http://dx.doi.org/10.1021/jacs.3c00581