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Tumor progression is independent of tumor-associated macrophages in cell lineage–based mouse models of glioblastoma

Macrophage targeting therapies have had limited clinical success in glioblastoma (GBM). Further understanding the GBM immune microenvironment is critical for refining immunotherapeutic approaches. Here, we use genetically engineered mouse models and orthotopic transplantation-based GBM models with i...

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Detalles Bibliográficos
Autores principales: Chipman, Mollie E., Wang, Zilai, Sun, Daochun, Pedraza, Alicia M., Bale, Tejus A., Parada, Luis F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10120014/
https://www.ncbi.nlm.nih.gov/pubmed/37040416
http://dx.doi.org/10.1073/pnas.2222084120